The present invention relates to a method for the generation of immunoglobulin molecules of predetermined specificity. In particular, the invention relates to a method for the retargeting of the epitope binding specificity of one or more antibodies using single variable domains which exhibit a dominant epitope binding specificity.
申请公布号
WO2004058822(A2)
申请公布日期
2004.07.15
申请号
WO2003GB05657
申请日期
2003.12.24
申请人
DOMANTIS LIMITED;WINTER, GREG;TOMLINSON, IAN;IGNATOVICH, OLGA