摘要 |
<P>PROBLEM TO BE SOLVED: To provide a substrate, which offers a more convenience in handling, easier cutting/sutures to arbitrary shapes and sizes, and improves cell reproduction rate etc., for regenerating cartilage tissues by cell cultivation. <P>SOLUTION: This substrate for cartilage cultivation is made of crosslinked collagen sponge combined with a reinforcement of a biodegradable absorbence. It is manufactured in the process of pouring an aqueous solution of collagen, its mixed solution with acetic acid/ethanol, or bubble solution of those onto the reinforcement laid down, and freeze-drying them. <P>COPYRIGHT: (C)2004,JPO&NCIPI |