| 发明名称 |
INHIBITORS OF THE BINDING OF CHEMOKINES I-TAC OR SDF-1 TO THE CCXCKR2 RECEPTOR |
| 摘要 |
Pharmaceutical compositions containing organic compounds of formula I or salts thereof that serve as modulators for the SDF-1 or I-TAC chemokines are disclosed. The compounds and compositions are useful in the treatment of cancer, especially in the inhibition of cancer proliferation, growth, and metastasis. Methods of interfering with SDF-1 and/or I-TAC binding to the CCXCKR2 receptor and treating cancer using the compounds and pharmaceutical compositions of the present invention are also disclosed. |
| 申请公布号 |
WO2004058705(A2) |
申请公布日期 |
2004.07.15 |
| 申请号 |
WO2003US41024 |
申请日期 |
2003.12.22 |
| 申请人 |
CHEMOCENTRYX |
发明人 |
MELIKIAN ANITA;BURNS JENNIFER;MCMASTER BRIAN E;SCHALL THOMAS;WRIGHT J J |
| 分类号 |
C07D207/06;C07D207/08;C07D207/09;C07D207/12;C07D207/14;C07D207/16;C07D211/14;C07D211/42;C07D211/56;C07D241/04;C07D241/42;C07D295/13;C07D401/04;C07D401/06;C07D405/04;C07D405/06;C07D405/12;C07D405/14;(IPC1-7):C07D207/09;C07D407/12;C07D407/04;C07D295/04;C07D211/26 |
主分类号 |
C07D207/06 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
