发明名称 Measurement of liquid phase gastric emptying
摘要 <p>Measuring gastric emptying of a liquid phase meal comprises: either: (a) preparing an edible alga of single cell organisms several microns in diameter, -labelled with a C-isotope, by photosynthesis; (b) suspending the algae in a liquid; (c) allowing a patient to consume the liquid algae so that the C-labelled nutrients are unable to penetrate the gastric mucosa and are absorbed in the small intestine and oxidised to labelled CO2, and (d) detecting the level of labelled CO2 in breath samples taken from the patient at periodic intervals, or (a') preparing a biscuit having a calorie content of 150; (b') preparing a drink to be consumed with the biscuit where a quantity of NC algae comprising single celled photosynthetic organisms of several microns diameter are suspended in a liquid so that the single celled photosynthetic organisms are unable to penetrate the gastric mucosa; (c') allowing a patient to consume the biscuit, a package of cream cheese and the drink as a meal of calorific value 340, so that the meal empties form the stomach into the small intestine where the labelled C is digested, absorbed and oxidised to labelled 13CO2 or 14CO2, and (d') taking periodic breath samples from the patient. Also claimed is a drink to be consumed by a patient for a gastric emptying test which comprises single celled photosynthetic organisms (which have been grown in 13CO2 or 14CO2) suspended in fruit juice having a predetermined caloric value, so that the organisms are unable to penetrate the gastric mucosa and thus pass into the small intestine with the liquid phase so that when oxidised, after digestion and absorption in the small intestine, a detectable rise in the 13CO2 or 14CO2 content of the patient's breath is produced.</p>
申请公布号 EP1437146(A1) 申请公布日期 2004.07.14
申请号 EP20040006804 申请日期 1997.08.19
申请人 ADVANCED BREATH DIAGNOSTICS LLC 发明人 KLEIN, PETER D.
分类号 A61K51/12;(IPC1-7):A61K51/12 主分类号 A61K51/12
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