发明名称 |
METHOD OF PRODUCING ELASTIN, ELASTIN-BASED BIOMATERIALS AND TROPOELASTIN MATERIALS |
摘要 |
A method is provided for producing elastin or elastin-based materials or tropoelastin materials which have a substantially reduced level of calcification. These materials are typically capable of being formed into a fused layer. The subject method comprises providing unreacted elastin or elastin-based biomaterials or tropoelastin materials, and pretreating the unreacted elastin or elastin-based biomaterials or tropoelastin materials with an aliphatic alcohol prior to reaction thereof. In this way, when the pretreated unreacted elastin or elastin-based biomaterials or tropoelastin materials is reacted subsequently, elastin or elastin-based materials or tropoelastin materials are produced which have a substantially reduced level of calcification as compared with elastin or elastin-based materials or tropoelastin materials produced from non-pretreated counterpart unreacted elastin or elastin-based biomaterials or tropoelastin materials. |
申请公布号 |
EP1049482(A4) |
申请公布日期 |
2004.07.14 |
申请号 |
EP19980966114 |
申请日期 |
1998.12.29 |
申请人 |
PROVIDENCE HEALTH SYSTEM-OREGON;GREGORY, KENTON W. |
发明人 |
GREGORY, KENTON, W. |
分类号 |
A61F2/00;A61F2/04;A61F2/06;A61F2/82;A61F2/90;A61K38/00;A61L27/22;A61L27/36;A61L27/38;A61L27/50;A61L31/00;A61L31/04;A61L31/14;B32B5/02;B32B9/02;C07K14/78;(IPC1-7):A61K38/17;A61F13/00;A61F2/02;A61F2/54 |
主分类号 |
A61F2/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|