发明名称 |
Method for the identification of microorganisms by mass spectrometry |
摘要 |
Identifying microorganisms (A) by mass spectrometry (MS). Identifying microorganisms (A) by mass spectrometry (MS) comprises: (1) establishing a database (DB) that contains: (a) synthetic reference spectra (REFs) of known (A), produced by compiling a number of specific signals (S) for each (A), where this number is fewer than the total number of signals in the natural reference spectrum (REFn); and (b) difference spectra (DIF) formed from any two REFs for known (A); (2) performing similarity analysis of a sample mass spectrum (SAM) of the organism being identified with REFs in DB; and (3) performing similarity analysis of SAM with at least some of the DIF in DB. An Independent claim is also included for a database for the process.
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申请公布号 |
EP1437673(A1) |
申请公布日期 |
2004.07.14 |
申请号 |
EP20030090419 |
申请日期 |
2003.12.03 |
申请人 |
ANAGNOSTEC, GESELLSCHAFT FUER ANALYTISCHE BIOCHEMIE UND DIAGNOSTIK MBH |
发明人 |
KALLOW, WIBKE;DIECKMANN, RALF;ERHARD, MARCEL;SAUERMANN, STEFAN |
分类号 |
C12Q1/04;(IPC1-7):G06F19/00;G06F17/30;G01N33/68 |
主分类号 |
C12Q1/04 |
代理机构 |
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