发明名称 |
ANTISENSE MODULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2 EXPRESSION |
摘要 |
<p>Antisense compounds, compositions and methods are provided for modulating the expression of vascular endothelial growth factor receptor-2. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding vascular endothelial growth factor receptor-2. Methods of using these compounds for modulation of vascular endothelial growth factor receptor-2 expression and for treatment of diseases associated with expression of vascular endothelial growth factor receptor-2 are provided.</p> |
申请公布号 |
EP1436310(A1) |
申请公布日期 |
2004.07.14 |
申请号 |
EP20020763756 |
申请日期 |
2002.09.26 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
BENNETT, C., FRANK;WATT, ANDREW, T. |
分类号 |
A61K38/00;C12N5/02;C12N15/113;(IPC1-7):C07H21/04;C12N15/86;A61K48/00;C12N15/11;C12N15/85;C12Q1/68;C07H21/02;C12P19/34 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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