发明名称 TRANSDUCTIN-1 AND TRANSDUCTIN-2 AND APPLICATIONS TO HEREDITARY DEAFNESS
摘要 The invention provides methods of detecting hearing loss or a predisposition to hearing loss in an animal, which comprises detecting at least one mutation in a gene encoding transduction-1 (TDC1) in a test sample obtained from the animal. The invention also provides a method of determining the level of nucleic acid comprising a wild-type TDC1 gene and/or a mutant TDC1 gene in a test sample obtained from an animal.
申请公布号 EP1436418(A2) 申请公布日期 2004.07.14
申请号 EP20020761716 申请日期 2002.09.19
申请人 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 发明人 GRIFFITH, ANDREW, J.;KURIMA, KIYOTO;WILCOX, EDWARD;FRIEDMAN, THOMAS
分类号 G01N33/53;A61K31/7052;A61K35/12;A61K38/00;A61K48/00;A61P27/16;C07H21/04;C07K14/47;C07K14/705;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/08;C12Q1/68;G01N33/566;(IPC1-7):C12Q1/68;C12P19/34 主分类号 G01N33/53
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