摘要 |
The present invention relates to a method for the preparation of citalopram or any of its enantiomers and acid addition salts thereof comprising reaction of a compound of formula IIwith a diene having the formulawherein X is O, S, SO2, -N=N-, -CO-O-, -O-CO-, oror with a diene having the formulawherein R is alkyl or optionally substituted aryl or arylalkyl.The invention also relates to intermediates used in the new process for the preparation of citalopram, as well as citalopram prepared according to the new process.
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