| 发明名称 |
ASYMMETRIC SYNTHESIS OF PREGABALIN |
| 摘要 |
This invention provides a method of making (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid (pregabalin) or a salt thereof via an asymmetric hydrogenation synthesis. Pregabalin is useful for the treatment and prevention of seizure disorders, pain, and psychotic disorders. The invention also provides intermediates useful in the production of pregabalin. |
| 申请公布号 |
PL357077(A1) |
申请公布日期 |
2004.07.12 |
| 申请号 |
PL20010357077 |
申请日期 |
2001.01.11 |
| 申请人 |
WARNER-LAMBERT CO. |
发明人 |
BURK MARK JOSEPH;GOEL OM PRAKASH;HOEKSTRA MARVIN SIMON;MICH THOMAS FREDERICK;MULHERN THOMAS ARTHUR;RAMSDEN JAMES ANDREW |
| 分类号 |
C07B53/00;C07B61/00;C07C227/04;C07C227/10;C07C229/08;C07C253/30;C07C255/19;C07C255/23 |
主分类号 |
C07B53/00 |
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