发明名称 PROTEIN CORRESPONDING TO NEISSERIA MENINGITIDIS ANTIGEN PROTEIN AND ELICITING IMMUNOGENIC PROPERTIES (VARIANTS), ANTIBODY BINDING WITH IT, NUCLEOTIDE SEQUENCE (VARIANTS) AND PHARMACEUTICAL COMPOSITION COMPRISING THEREOF
摘要 FIELD: molecular biology, immunology, microbiology, pharmacy. ^ SUBSTANCE: invention represents proteins of meningococcus bacterium Neisseria meningitides (strains A and B) and Neisseria gonorrhoeae. Amino acid sequences of claimed proteins are represented in the description. Corresponding nucleotide sequences encoding the claimed proteins are represented also. Represented proteins are components of vaccines, immunogenic compositions as antigens and (or) can be used for diagnostic aims. Invention claims an antibody that binds with indicated protein. Invention provides enhancing the effectiveness of preparations used for diagnosis, treatment and prophylaxis of infections caused by Neisseria meningitides and Neisseria gonorrhoeae. ^ EFFECT: valuable medicinal properties of protein and composition. ^ 12 cl, 2 tbl, 104 ex
申请公布号 RU2232191(C2) 申请公布日期 2004.07.10
申请号 RU20000114245 申请日期 1998.10.09
申请人 发明人 MAZIN'JANI VEGA;RAPPUOLI RINO;PITSTSA MARIJAGRATSIJA;SKARLATO VINCHENTSO;GRANDI GVIDO
分类号 C12N15/31;A61K39/095;C07K14/22;C12R1/36 主分类号 C12N15/31
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