PROCESS FOR PREPARING ARIPIPRAZOLE

摘要

The present invention provides a process for preparing aripiprazole in a high purity and a high yield. According to the process of the present invention, aripiprazole is prepared by the reaction of a carbostyril compound represented by general formula (2): <IMG> (wherein X is halogen atom, lower alkanesulfonyloxy group, arylsulfonyloxy group or an aralkylsulfonyloxy group), with a piperazine compound represented by formula (3): <IMG> and/or a salt thereof in water, in the presence of 0.5 to 10 mol of an inorganic basic compound, per mol of the carbostyril compound (2).