发明名称 |
OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS |
摘要 |
<p>A compound of the formula (I), or a pharmaceutically-acceptable salt, or in-vivo hydrolysable ester thereof: (I)wherein in (I) C is for example wherein A and B are independently selected from i) ii) and m is 1 or 2;R2b and R6b, R2a and R6a, R3a and R5a, are for example selected from H, F, OMe and Me;R2b' and R6b', R2a' and R6a', R3a', R5a' are for example selected from H, OMe and Me;R1a is for example optionally substituted (1-10C)alkyl;R1b is for example selected from NR5C(=W)R4, a) , or b) wherein HET-1 is for example isoxazolyl and HET-2 is for example triazolyl or tetrazolyl.Methods for making compounds of the formula (I), compositions containing them and their use as antibacterial agents are also described.</p> |
申请公布号 |
WO2004056817(A1) |
申请公布日期 |
2004.07.08 |
申请号 |
WO2003GB05448 |
申请日期 |
2003.12.15 |
申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;GRAVESTOCK, MICHAEL, BARRY;HALES, NEIL, JAMES;HUYNH, HOAN, KHAI |
发明人 |
GRAVESTOCK, MICHAEL, BARRY;HALES, NEIL, JAMES;HUYNH, HOAN, KHAI |
分类号 |
C07D413/14;C07D417/14;(IPC1-7):C07D413/14;A01N43/80;A01N43/78 |
主分类号 |
C07D413/14 |
代理机构 |
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