Methods and compositions for inhibiting immunoglobulin-mediated reperfusion injury

摘要

Methods and compositions for treating or preventing immunoglobulin-mediated reperfusion or ischemic injury, in a subject, are provided. Methods for identifying inhibitors of an interaction between a pathogenic immunoglobulin and ischemic antigen or a component of the complement pathway are provided. Pathogenic immunoglobulin and mutated forms thereof are also disclosed