发明名称 |
ANTIBODIES AGAINST PD-1 AND USES THEREFOR |
摘要 |
<p>This disclosure provides antibodies and antigen-binding fragments that can a ct as agonists and/or antagonists of PD-1 (Programmed Death 1), thereby modulating immune responses in general, and those mediated by TcR and CD28, in particular. The disclosed compositions and methods may be used for example, in treating autoimmune diseases, inflammatory disorders, allergies, transplant rejection, cancer, and other immune system disorders.</p> |
申请公布号 |
CA2508660(A1) |
申请公布日期 |
2004.07.08 |
申请号 |
CA20032508660 |
申请日期 |
2003.12.22 |
申请人 |
WYETH;CAMBRIDGE ANTIBODY TECHNOLOGY LIMITED |
发明人 |
CARRENO, BEATRIZ M.;COLLINS, MARY;ANDREWS, JOHN;RUSSELL, CAROLINE;CARTER, LAURA L.;BENNETT, FRANCES K.;VALGE-ARCHER, VIIA;WOOD, CLIVE R.;JUSSIF, JASON;LUXENBERG, DEBORAH |
分类号 |
A61P37/06;C07K16/28;C12N15/13;(IPC1-7):C07K16/28;A61K39/395;C12N15/63;C12N5/10 |
主分类号 |
A61P37/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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