| 发明名称 |
PROCESS FOR THE PREPARATION OF AN ESSENTIALLY PURE POLYMORPHOF AN N-PYRAZOLYL-N'-NAPHTHYL-UREA |
| 摘要 |
The invention relates to an improved process for the preparation of a polymorph of 1-[tert-butyl-1-p-tolyl-1H-pyrazol-5-yl]-3-[4-(2-morpolinin-4-y l- ethoxy)naphthalen-1-yl]-urea (1) by crystallization from an alcohol, wherein the improvement is that crude (1) is treated with ethanol.
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| 申请公布号 |
CA2511325(A1) |
申请公布日期 |
2004.07.08 |
| 申请号 |
CA20032511325 |
申请日期 |
2003.12.12 |
| 申请人 |
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG |
发明人 |
KOCH, GUNTER;SAMSTAG, WENDELIN |
| 分类号 |
A61P37/00;C07D231/40;(IPC1-7):C07D231/40;A61K31/415 |
主分类号 |
A61P37/00 |
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