| 发明名称 |
MEK INHIBITING OXA- AND THIA-DIAZOL-2-YL PHENYLAMINE DERIVATIVES |
| 摘要 |
This invention provides substituted Phenyl-(2-[1,3,4]thiadiazol-2-yl~phenyl) - amine and (2-[1,3,4]Oxadiazol-2-yl-phenyl)phenyl-amine compounds which act a s inhibitors of MAPKIERK Kinase ("MEK") enzymes and pharmaceutical composition s and methods for their use in immunomodulation and in the treatment and alleviation of inflammation, and proliferative diseases such as cancer and restenosis.
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| 申请公布号 |
CA2509405(A1) |
申请公布日期 |
2004.07.08 |
| 申请号 |
CA20032509405 |
申请日期 |
2003.12.08 |
| 申请人 |
WARNER-LAMBERT COMPANY LLC |
发明人 |
REED, JESSICA ELIZABETH;BARRETT, STEPHEN DOUGLAS;KAUFMAN, MICHAEL DAVID;PLUMMER, MARK STEPHEN;BIWERSI, CATHLIN MARIE;WARMUS, JOSEPH SCOTT;ZHANG, LU YAN |
| 分类号 |
A61P29/00;A61P35/00;C07D249/08;C07D249/14;C07D271/10;C07D271/113;C07D285/12;C07D285/135;C07D413/04;C07D413/12;C07D413/14;C07D417/14;(IPC1-7):C07D271/113;A61K31/424 |
主分类号 |
A61P29/00 |
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