| 发明名称 |
MELUSIN, A MUSCLE SPECIFIC PROTEIN, AS A DRUG TARGET FOR PREVENTION AND TREATMENT OF HEART FAILURE |
| 摘要 |
The present invention concerns non-human transgenic animals as model study f or human pathologies, being transgenic for having altered melusin expression. T he non-human transgenic animals are to be used as models to study heart pathologies and provide therapies thereof, wherein the heart pathologies are heart failure, and in particular diluted cardiomyopathy.
|
| 申请公布号 |
CA2505374(A1) |
申请公布日期 |
2004.07.08 |
| 申请号 |
CA20022505374 |
申请日期 |
2002.12.19 |
| 申请人 |
UNIVERSITA' DEGLI STUDI DI TORINO |
发明人 |
TARONE, GUIDO;ALTRUDA, FIORELLA;LEMBO, GIUSEPPE;FRATTA, LUIGI;BRANCACCIO, MARA;SILENGO, LORENZO |
| 分类号 |
A61K48/00;C07K14/46;C12N15/85;(IPC1-7):A01K67/027;A61K38/17;C07K14/47;G01N33/50 |
主分类号 |
A61K48/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
