| 摘要 |
Nanoscale field effect transistor devices with carbon nanotubes as the conducting channel are used to detect protein-protein binding. A coating of an electron-donating polymer is applied to a nanotube device, and a receptor compound is bound to the polymer. The receptor compound is configured to bind a specific biological molecule or molecules. The device coated with the polymer coating and receptor compound may be operated as a p-type field-effect transducer. For example, upon exposure to biological molecules bound by the receptor, the conductance at negative voltage may be markedly reduced, thereby establishing an electronic signal response.
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