HUMAN VARIANTS OF KALLIKREIN-2 AND KALLIKREIN-3 AND USES THEREOF

摘要

The invention concerns the field of biology, genetics and medicine. It concerns in particular novel methods for detecting, characterizing and/or treating cancer pathologies, in particular prostatic cancer. The invention also concerns methods for identifying or screening compounds active in said pathologies. The invention further concerns compounds, genes, cells, plasmids or compositions useful for implementing said methods. The invention concerns in particular the role of human variants of kallikrein-2 and kallikrein-3, also referred to as PSA, in said pathologies and their uses as therapeutic, diagnostic or experimental targets.