摘要 |
<p>The invention relates to a new method for preparing norbenzomorphane derivatives of general formula (1), wherein R1 is H, C1-C8alkyl group, C1-C8alkoxy group, hydroxy group, halogen wherein 4-methylenepriperidine derivative is transformed by the acid to related additive salt with an acid, which reacts in reaction medium with aluminous halogenide, preferably with aluminous bromide or aluminous chloride, under the temperature in interval from 0 to 150 °C and the reaction product is isolated after the realisation of the reaction.</p> |