发明名称 Improved method for preparing pharmaceutically valuable norbenzomorphane derivatives
摘要 <p>The invention relates to a new method for preparing norbenzomorphane derivatives of general formula (1), wherein R1 is H, C1-C8alkyl group, C1-C8alkoxy group, hydroxy group, halogen wherein 4-methylenepriperidine derivative is transformed by the acid to related additive salt with an acid, which reacts in reaction medium with aluminous halogenide, preferably with aluminous bromide or aluminous chloride, under the temperature in interval from 0 to 150 °C and the reaction product is isolated after the realisation of the reaction.</p>
申请公布号 SK283996(B6) 申请公布日期 2004.07.07
申请号 SK20000001731 申请日期 1999.05.07
申请人 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG 发明人 GRAUERT MATTHIAS;BALTES HANFRIED;SCHNAUBELT JURGEN
分类号 C07D221/06;C07D221/22;C07D221/26;(IPC1-7):C07D221/26 主分类号 C07D221/06
代理机构 代理人
主权项
地址