发明名称 Single-chain multiple antigen-binding molecule, its preparation and use
摘要 The present invention relates to a single-chain, multiple antigen-binding molecule with diverse variable domains of a heavy and of a light chain of an immunoglobulin, which are connected in the form of a VH-VL construct, which are in turn connected together via a peptide, and to the preparation and use thereof as pharmaceutical or diagnostic aid.
申请公布号 US6759518(B1) 申请公布日期 2004.07.06
申请号 US19990288719 申请日期 1999.04.09
申请人 VECTRON THERAPEUTICS AG 发明人 KONTERMANN ROLAND;SEDLACEK HANS-HARALD;MUELLER ROLF
分类号 C12N15/00;A61K31/00;A61K35/74;A61K35/76;A61K38/00;A61K39/00;A61K48/00;A61P7/00;A61P25/00;A61P31/00;A61P35/00;A61P37/00;C07K16/00;C07K16/30;C07K16/40;C07K16/46;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12N15/13;(IPC1-7):C07K16/00;C12P21/08;C12N15/63 主分类号 C12N15/00
代理机构 代理人
主权项
地址