| 发明名称 |
High affinity RNA ligands of basic fibroblast growth factor |
| 摘要 |
Methods are described for the identification and preparation of nucleic acid ligand solutions to basic fibroblast growth factor (bFGF). Included in the invention are nucleic acid ligands to bFGF which are inhibitors of bFGF and 2'-amino-modified RNA ligands to bFGF.
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| 申请公布号 |
US6759392(B1) |
申请公布日期 |
2004.07.06 |
| 申请号 |
US19950442423 |
申请日期 |
1995.05.16 |
| 申请人 |
GILEAD SCIENCES, INC. |
发明人 |
JANJIC NEBOJSA;GOLD LARRY |
| 分类号 |
C07B61/00;C07H19/06;C07H19/10;C07H21/00;C07K14/00;C12N9/12;C12N15/10;C12N15/113;C12N15/115;C12Q1/37;C12Q1/68;C12Q1/70;F02B75/02;G01N33/531;G01N33/532;G01N33/535;G01N33/569;G01N33/68;G01N33/76;(IPC1-7):A01N43/04;A61K31/70 |
主分类号 |
C07B61/00 |
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