| 摘要 |
<p>An object of the present invention is to find new pharmacological actions of urea compounds having structure represented by the general formula Ä1Ü. The urea compounds having the structure represented by the general formula Ä1Ü have excellent angiogenesis inhibitory actions. <CHEM> Äwherein "A" is -(NR<4>)-, -(CR<5>R<6>)- or -O-, "B" is alkylene or alkenylene, R<1>, R<2>, R<4>, R<5> and R<6> are hydrogen, alkyl, alkenyl, adamantylalkyl or the like, R<3> is aryl or an unsaturated heterocycle, and X is oxygen or sulfur.Ü</p> |
