摘要 |
Process for the preparation of (1S, 4R)-4-hydroxy cyclopent-2-enyl esters comprising the steps of: a) reacting a cis-cyclopent-1-ene-3,5-diol, or racemic or a partially resolved 4-hydroxy cyclopent-2-enyl ester, with a suitable ester donor in the presence a lipase from Alcaligenes sp. and b) recovering and purifying the produced (1S, 4R)-4-hydroxy cyclopent-2-enyl ester. The reaction is preferably carried out at a temperature in the range from 10° C. to room temperature.
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