CONTROLLED RELEASE PREPARATIONS COMPRISING TRAMADOL AND TOPIRAMATE
摘要
This invention relates to an oral pharmaceutical preparation, suitable for dosing every 24 hours, comprising a substrate, which substrate comprises a pharmaceutically effective amount of tramadol or a salt thereof and a pharmaceutically effective amount of topiramate and wherein said substrate may be coated with a controlled release coating; said preparation having a specific dissolution rate in vitro.
申请公布号
WO2004054571(A1)
申请公布日期
2004.07.01
申请号
WO2003EP14474
申请日期
2003.12.12
申请人
CILAG AG;BACHMANN, DIETER;EIVASKHANI, REZA;BRAUN, CHRISTIAN;SPYCHER, RENE;STRONG, BRIAN
发明人
BACHMANN, DIETER;EIVASKHANI, REZA;BRAUN, CHRISTIAN;SPYCHER, RENE;STRONG, BRIAN