| 发明名称 |
4-SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION |
| 摘要 |
The invention relates to 6-substituted benzimidazoles of formula 1, in which X is O (oxygen) or NH and Y has either the meaning -CH2-Ar wherein Ar is a mon o- or bicyclic aromatic residue, or Y denotes the group gp, formula (gp) wherei n Z has the meaning -CHR8- or -CHR8-CHR9-. The compounds have gastric secretio n inhibiting and excellent gastric and intestinal protective action properties . |
| 申请公布号 |
CA2508838(A1) |
申请公布日期 |
2004.07.01 |
| 申请号 |
CA20032508838 |
申请日期 |
2003.12.11 |
| 申请人 |
ALTANA PHARMA AG |
发明人 |
BUHR, WILM;KROMER, WOLFGANG;BREHM, CHRISTOF;PALMER, ANDREAS;CHIESA, VITTORIA;SIMON, WOLFGANG-ALEXANDER;POSTIUS, STEFAN;SENN-BILFINGER, JORG;ZIMMERMANN, PETER JAN;GRUNDLER, GERHARD |
| 分类号 |
A61K31/4184;A61K31/422;A61K31/4245;A61P1/04;C07D235/06;C07D235/08;C07D235/12;C07D403/04;C07D403/06;C07D413/04 |
主分类号 |
A61K31/4184 |
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