发明名称 METHODS FOR SPECIFICALLY INHIBITING HISTONE DEACETYLASE-7 AND 8
摘要 This invention relates to the inhibition of histone deacetylase (HDAC) expression and enzymatic activity. The invention provides methods and reagents for inhibiting HDAC-7 and HDAC-8 by inhibiting expression at the nucleic acid level or inhibiting enzymatic activity at the protein level.
申请公布号 WO2004005513(A3) 申请公布日期 2004.07.01
申请号 WO2003IB03052 申请日期 2003.06.12
申请人 METHYLGENE, INC. 发明人 BESTERMAN, JEFFREY, M.;LI, ZUOMEI;DELORME, DANIEL;BONFILS, CLAIRE
分类号 A61K31/167;A61K31/4015;A61K31/505;A61K31/5377;A61K31/7088;A61K38/00;C07C237/20;C07C237/40;C07C323/44;C07D209/48;C07D213/73;C07D235/28;C07D239/42;C07D277/82;C07D295/135;C07D317/66;C12N15/113 主分类号 A61K31/167
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