发明名称 N-(INDOLETHYL-)CACLOAMINE COMPOUNDS
摘要 The invention relates to n-(indolethyl-)cacloamine compounds of a formula (i ), wherein R1, R1 x, Ar and n have a meaning of the claim 1. The inventive compounds consist of inhibitors of serotonin recapture (SSRI) and activators of serotoninenergic receptors 5-HT1A and 5-HT2A. Said compounds are used for preventing and treating various diseases of the central nervous system such as depression, dyskenesia, Parkinson's disease, dementia, vascular cerebral accident, schizophrenia, Alzheimer disease, Lewy bodies dementia, Huntington disease, Gille de la Tourette syndrome, anxiety, learning difficulties, memo ry disorder, pain, insomnia and neurodegenerative diseases.
申请公布号 CA2510169(A1) 申请公布日期 2004.07.01
申请号 CA20032510169 申请日期 2003.11.27
申请人 MERCK PATENT GMBH 发明人 SEYFRIED, CHRISTOPH;LEIBROCK, JOACHIM;BARTOSZYK, GERD;VAN AMSTERDAM, CHRISTOPH;HEINRICH, TIMO;BOETTCHER, HENNING;SCHIEMANN, KAI;HOELZEMANN, GUENTER
分类号 A61P43/00;C07D209/14;C07D209/18;C07D209/42;C07D405/12;C07D417/12;(IPC1-7):C07D209/14;A61K31/404;A61K31/495 主分类号 A61P43/00
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