METHOD FOR GENERATING A GENETICALLY MODIFIED ORGANISM FOR SCREENING ACTIVE SUBSTANCES

摘要

The invention relates to a method for generating a genetically modified organism for screening active substances comprising the following steps: a) inducing the heterologous expression of at least one protein or protein fragment by genetic modification of the organism; b) analysis of the modifie d gene expression pattern and identification of genes that have undergone compensatory and differential regulation; and c) phenotyping of the organism . The invention also relates to a genetically modified organism that can be obtained by said method.