| 摘要 |
A composite (A) comprises: (1) a homogeneous mixture (A1) of at least one hydrophobic, nonionic polymer (I) and at least one hydrophilic polyether (II); and (2) at least one antibiotic salt (III) that is sparingly soluble in water. A composite (A) comprises: (1) a homogeneous mixture (A1) of at least one hydrophobic, nonionic polymer (I) and at least one hydrophilic polyether (II); and (2) at least one antibiotic salt (III) that is sparingly soluble in water. (I) is PVC, optionally post-chlorinated; poly(vinylidene chloride or fluoride), poly(vinyl fluoride) or a copolymer of vinyl chloride with at least one nonionic monomer. (III) is the salt of an aminoglycoside, lincosamide, tetracycline, glycopeptide or quinolone antibiotic, or of chlorhexidine. (A) may also include (i) an antibiotic (IV; aminoglycoside, lincosamide, beta-lactam or tetracycline) that is freely soluble in water and (ii) one or more organic auxiliaries. |
