| 摘要 |
A large conductance calcium-activated K channel opener comprising as an active ingredient a nitrogen-containing 5-membered heterocyclic compound represented by the following formula (I): wherein X represents N-R<4>, O or S, R<1 >and R<2 >each independently represent hydrogen, halogen, carboxyl, amino, lower alkyl, lower alkoxycarbonyl, lower alkenyl, cyclo-lower alkyl, carbamoyl, aryl, heterocyclic or heterocyclic-substituted carbonyl group, R<3 >represents aryl, heterocyclic or lower alkyl group, and R<4 >represents hydrogen or lower alkyl group, or a pharmaceutically acceptable salt thereof. |
