发明名称 METHOD FOR PREPARATION OF 10,11-DIHYDRO-10-HYDROXY-5H-DIBENZ/B,F/AZEPINE-5-CARBOXAMIDE AND 10,11-DIHYDRO-10-0X0-5H-DIBENZ/B,F/AZEPINE-5-CARBOXAMIDE.
摘要 <p>A method for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azepine-5-carboxamide and 10,11-dihydro-10-oxo-5H-dibenz/b,f/azepine-5-carboxamide from carbamazepine via a three-step process involving (i) epoxidation of carbamazepine; (ii) ring-opening of the resulting epoxide and (iii) oxidation of the resulting alcohol.</p>
申请公布号 MXPA03010793(A) 申请公布日期 2004.07.01
申请号 MX2003PA10793 申请日期 2002.05.22
申请人 PORTELA & C.A. S.A. 发明人 DAVID ALEXANDER LEARMONTH
分类号 A61P25/08;C07B61/00;C07D223/22;C07D491/04;C07D491/044;(IPC1-7):A61K31/55 主分类号 A61P25/08
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