SYNTHESIS OF 2 -DEOXY-L-NUCLEOSIDES.

摘要

This invention provides processes for the preparation of compounds having structure (A) wherein X and Y are same or different, and H, OH, OR, SH, SR, NH2, NHR , or NR R; Z is H, F, Cl, Br, I, CN or NH2. R is hydrogen, halogen, lower alkyl of C1-C6 or aralkyl, NO2, NH2, NHR , NR R, OH, OR, SH, SR, CN, CONH2, CSNH2, CO2H, CO2R , CH2CO2H, CH2CO2R , CH=CHR, CH2CH=CHR, or C=CR. R and R are same or different, and lower alkyl of C1-C6. R13 is hydrogen, alkyl, acyl, phosphate (monophosphate, diphosphate, triphosphate, or stabilized phosphate) or silyl.