Recombinant bovine pancreatic desoxyribonuclease I with high specific activity
摘要
A method is provided for the production of a bovine pancreatic protein with a specific desoxyribonuclease activity of at least 6,000 units per mg of protein. Methylotrophic yeast is used as a heterologous host organism. The bovine pancreatic protein is secreted into the growth medium from which it is purified. <IMAGE>
申请公布号
EP1433842(A1)
申请公布日期
2004.06.30
申请号
EP20030028841
申请日期
2003.12.16
申请人
ROCHE DIAGNOSTICS GMBH;F.HOFFMANN-LA ROCHE AG
发明人
MUELLER, RAINER, DR.;SUPPMANN, BERNHARD, DR.;THALHOFER, JOHANN-PETER, DR.;RONNING, STEPHANIE;SCHOEN, HELMUT, DR.