发明名称 TRIAZOLE DERIVATIVES USEFUL IN THERAPY
摘要 The invention provides compounds of formula I, <?in-line-formulae description="In-line Formulae" end="lead"?>R<SUP>1</SUP>-OP(O)(OH)<SUB>2</SUB> I<?in-line-formulae description="In-line Formulae" end="tail"?> wherein R<SUP>1 </SUP>represents the non-hydroxy portion of a triazole antifungal compound of the type comprising a tertiary hydroxy group; or a pharmaceutically acceptable salt thereof. The compounds of the invention are useful in the treatment of fungal infections, and have good aqueous solubility.
申请公布号 PL187237(B1) 申请公布日期 2004.06.30
申请号 PL19970328436 申请日期 1997.01.27
申请人 PFIZER RESEARCH AND DEVELOPMENT CO,NV /S.A. 发明人 GREEN STUART;STEPHENSON PETER T.;MURTIASHAW CHARLES W.
分类号 C07D249/08;A61K31/00;A61K31/4196;A61K31/425;A61K31/675;A61P17/00;A61P31/00;A61P31/10;C07D403/10;C07D417/10;C07F;C07F9/6518;C07F9/6521;C07F9/6558 主分类号 C07D249/08
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