| 摘要 |
An implantable keratoprosthesis having a central lenticule and a peripheral annulus of corneal tissue. The keratoprosthesis includes a transparent polymeric lenticule having an elongated stem with a generally cylindrical outer surface and a central axis. On one end thereof, the stem carries a dome having a peripheral skirt extending outwardly from the axis beyond the cylindrical surface of the stem. An annulus of corneal tissue has a central bore within which the stem is received, the peripheral skirt contacting and overlying a portion of the corneal annulus adjacent the bore. A portion of the annulus extends outwardly beyond the peripheral skirt for attachment to a surgically prepared cornea. A ring of polymeric material is received over the stem to capture between the ring and the skirt the corneal annulus. The ring is attached to the stem, as by welding and/or by use of a tissue-adherent, biologically acceptable adhesive disposed between the cylindrical surface of the stem and the bore of the annulus to form a strong, liquid-tight seal between the stem and annulus.
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