| 发明名称 |
ПОЛИМЕР-МОДИФИЦИРОВАННЫЕ БИОАКТИВНЫЕ СИНТЕТИЧЕСКИЕ ХЕМОКИНЫ И СПОСОБЫ ИХ ПРИГОТОВЛЕНИЯ И ПРИМЕНЕНИЯ |
| 摘要 |
The invention relates to polymer-modified bioactive synthetic chemokines and to methods for their production and use. The bioactive synthetic chemokines of the invention comprises a polymer modified polypeptide chemokine backbone. The compounds and methods or the invention are useful for the treatment of disorders involving naturally occurring chemokines, such as for the treatment of HIV and AIDS related disorders and for the treatment of asthma, allergic rhinitis, atopic dermatitis, atheroma/atherosclerosis, organ transplant rejection, and rheumatoid arthritis. |
| 申请公布号 |
RU2003104024(A) |
申请公布日期 |
2004.06.27 |
| 申请号 |
RU20030104024 |
申请日期 |
2001.07.12 |
| 申请人 |
ГРИФОН ТЕРАПЬЮТИКС, ИНК. (US) |
发明人 |
БРЭДБЕРН Джеймс А. (US);КОХЕНДЕРФЕР Герд Г. (US);УИЛКЕН Джилл Дж. (US) |
| 分类号 |
A61K47/30;A61K38/00;A61K38/19;A61K45/00;A61K47/34;A61K47/48;A61P9/10;A61P11/06;A61P17/00;A61P27/16;A61P29/00;A61P35/00;A61P37/00;A61P37/08;C07H21/04;C07K14/47;C07K14/52;C07K14/715;C07K19/00;C12P21/02 |
主分类号 |
A61K47/30 |
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