Compositions and methods for treating pancreatic cancer

摘要

The present invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a K-ras oncogene, comprising a complementary RNA strand which is substantially identical to at least a part of a K-ras gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of a K-ras oncogene using the pharmaceutical composition; and methods for inhibiting the expression of a K-ras oncogene in a cell.