| 发明名称 |
Pharmaceutical compositions and dosage forms for buccal and sublingual delivery of tizanidine and methods of administering tizanidine sublingually or buccally |
| 摘要 |
Sublingual and buccal administration of the muscle spasm suppressor tizanidine increase its bioavailability by avoiding first-pass metabolism in the liver and reduce the inter-patient variation in bioavailability.
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| 申请公布号 |
US2004122065(A1) |
申请公布日期 |
2004.06.24 |
| 申请号 |
US20030699991 |
申请日期 |
2003.11.03 |
| 申请人 |
LERNER E. ITZHAK;FLASHNER-BARAK MOSHE;ROSENBERGER VERED |
发明人 |
LERNER E. ITZHAK;FLASHNER-BARAK MOSHE;ROSENBERGER VERED |
| 分类号 |
A61K9/00;A61K9/20;A61K9/28;A61K31/4168;A61K31/4178;A61K31/433;(IPC1-7):A61K31/433 |
主分类号 |
A61K9/00 |
| 代理机构 |
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代理人 |
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