| 发明名称 |
Antitubulin assembly and cell growth inhibitor denominated dioxostatin |
| 摘要 |
A new inhibitor of microtubule assembly (IC50 0.59 muM); with antineoplastic properties, denominated "dioxostatin", has been synthesized and its effectiveness against human cancer and murine P388 lymphocytic leukemia cell lines demonstrated. Dioxostatin hs the following structure (I).
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| 申请公布号 |
US2004122083(A1) |
申请公布日期 |
2004.06.24 |
| 申请号 |
US20030275789 |
申请日期 |
2003.03.31 |
| 申请人 |
PETTIT GEORGE R;LIPPERT JOHN W |
发明人 |
PETTIT GEORGE R;LIPPERT JOHN W |
| 分类号 |
A61K31/357;A61K36/18;A61P9/00;A61P17/06;A61P27/02;A61P27/06;A61P35/00;C07D317/22;(IPC1-7):C07D323/02 |
主分类号 |
A61K31/357 |
| 代理机构 |
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