| 发明名称 |
CYANOMETHYL DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS |
| 摘要 |
The present invention is directed to cyanomethyl derivatives that are inhibitors of cysteine protease, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. T he present invention is directed to pharmaceutical compositions comprising thes e compounds and processes for preparing them.
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| 申请公布号 |
CA2506114(A1) |
申请公布日期 |
2004.06.24 |
| 申请号 |
CA20032506114 |
申请日期 |
2003.11.26 |
| 申请人 |
AXYS PHARMACEUTICALS |
发明人 |
LINK, JOHN O.;LIU, YANG;MOSSMAN, CRAIG J.;ZIPFEL, SHEILA M.;PATTERSON, JOHN W.;GRAUPE, MICHAEL;LAU, AGNES J. |
| 分类号 |
A61K38/00;A61P35/00;C07K5/078;(IPC1-7):C07K5/062;A61K38/05 |
主分类号 |
A61K38/00 |
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