| 发明名称 |
ANHYDROUS CRYSTALLINE AZIDO CYTOSINE HEMISULFATE DERIVATIVE |
| 摘要 |
<p>The present invention relates to the hemisulfate salt of 1-[4(S)-azido-2(S),3(R)-dihydroxy-4-(hydroxymethyl)-1(R)-cyclopentyl]cytosine (Ia) with improved stability and physical properties which facilitate manufacturing, handling and formulating (I) and polymorphic crystalline forms thereof.</p> |
| 申请公布号 |
WO2004052906(A1) |
申请公布日期 |
2004.06.24 |
| 申请号 |
WO2003EP13899 |
申请日期 |
2003.12.08 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
CONNOLLY, TERRENCE, JOSEPH;MARTIN, JOSEPH, ARMSTRONG;PRINCE, ANTHONY;SARMA, KESHAB |
| 分类号 |
A61K31/70;A61K31/7052;A61K31/7068;A61K31/7072;A61P31/12;C07H19/06;C07H19/067;(IPC1-7):C07H19/06;A61K31/706 |
主分类号 |
A61K31/70 |
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