PYRIDINE DERIVATIVES AS JNK INHIBITORS AND THEIR USE

摘要

The present invention relates to new compounds of formula (I) whrein: R<1> is aryl or heteroaryl, each of which is optionally substituted with one or more of R<3>, OR<3>, OCOR<3>, COOR<3>, COR<3>, CONR<3>R<4>, NHCOR<3>, NR<3>R<4>, NHSO2R<3>, SO2R<3>, SO2NR<3>R<4>, SR<3>, CN, halogeno or NO2; R<2> is R<5>, R<6>, COR<5>, COR<6>, CONHR<5>, CONHR<6>, CON(R<6>)2, COOR<5>, COOR<6>, SO2R<5> or SO2R<6>; a process for their preparation and new intermediates used therein, pharmaceutical formulations containing said therapeutically active compounds and to the use of said active compounds in therapy.