发明名称 |
ARYLENE-CARBOXYLIC ACID (2-AMINO-PHENYL)-AMIDE DERIVATIVES AS PHARMACEUTICAL AGENTS |
摘要 |
The present invention describes compounds of general formula (I), a process for their manufacture, medicaments containing them and their manufacture as well as the use of these compounds as pharmaceutical agents. The compounds according to this invention show antiproliferative and differentiation- inducing activity, which results in inhibition of tumor cell proliferation, induction of apoptosis and inhibition of invasion.
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申请公布号 |
CA2507137(A1) |
申请公布日期 |
2004.06.24 |
申请号 |
CA20032507137 |
申请日期 |
2003.12.09 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
REIFF, ULRIKE;WEIDNER, MICHAEL;LIMBERG, ANJA;KOERNER, MATTHIAS;KUBBIES, MANFRED;FERTIG, GEORG;HERTING, FRANK |
分类号 |
A61K31/165;A61K31/381;A61K31/44;A61P35/00;C07C233/77;C07C237/42;C07C275/24;C07D213/82;C07D333/38;(IPC1-7):C07C233/77 |
主分类号 |
A61K31/165 |
代理机构 |
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代理人 |
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地址 |
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