发明名称 ARYLENE-CARBOXYLIC ACID (2-AMINO-PHENYL)-AMIDE DERIVATIVES AS PHARMACEUTICAL AGENTS
摘要 The present invention describes compounds of general formula (I), a process for their manufacture, medicaments containing them and their manufacture as well as the use of these compounds as pharmaceutical agents. The compounds according to this invention show antiproliferative and differentiation- inducing activity, which results in inhibition of tumor cell proliferation, induction of apoptosis and inhibition of invasion.
申请公布号 CA2507137(A1) 申请公布日期 2004.06.24
申请号 CA20032507137 申请日期 2003.12.09
申请人 F. HOFFMANN-LA ROCHE AG 发明人 REIFF, ULRIKE;WEIDNER, MICHAEL;LIMBERG, ANJA;KOERNER, MATTHIAS;KUBBIES, MANFRED;FERTIG, GEORG;HERTING, FRANK
分类号 A61K31/165;A61K31/381;A61K31/44;A61P35/00;C07C233/77;C07C237/42;C07C275/24;C07D213/82;C07D333/38;(IPC1-7):C07C233/77 主分类号 A61K31/165
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