发明名称 |
Novel asymmetrical bicipital lipid and tubular aggregate formed by using the same |
摘要 |
The present invention offers a novel asymmetric double-headed lipid capable of forming a stable, nanometer scale micro-tubular aggregated material of containing a sugar and a carboxylic acid at each end. The present invention is an asymmetric double-headed lipid represented by the general formula R-NHCO-(CH2)n-COOH (I) (in the formula, R represents an aldopyranose radical from which the terminal reducing hydroxyl group is excluded and n is from six to twenty) and a hollow micro-tubular aggregated material formed from the asymmetric double-headed lipid. The external diameter of the micro-tubular aggregated material is 10-300 nm, and the length is 0.3-10 mum. The micro-tubular aggregated material can be manufactured by dispersing the asymmetric double-headed lipid described above in water at pH of two to eight, next heating to 80-100° C. to dissolve it and then gradually cooling the aqueous solution obtained.
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申请公布号 |
US2004120998(A1) |
申请公布日期 |
2004.06.24 |
申请号 |
US20030475700 |
申请日期 |
2003.10.20 |
申请人 |
MASUDA MITSUTOSHI;SHIMIZU TOSHIMI |
发明人 |
MASUDA MITSUTOSHI;SHIMIZU TOSHIMI |
分类号 |
C07H5/04;C07H13/06;(IPC1-7):A61K9/127 |
主分类号 |
C07H5/04 |
代理机构 |
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主权项 |
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地址 |
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