Drug-free biodegradable 3D porous collagen-glycosaminoglycan scaffold

摘要

A drug-free biodegradable 3D porous collagen-glycosaminoglycan scaffold is designed for preventing scar formation and creating a physiological aqua buffer environment around the conjuctival space for glaucoma. The scaffold improves the re-modeling of the regenerating tissue and prevents scar formation and further infection. It is prepared without further chemical linkage, and consequently becomes softer and without the uncertainty of chemical remnants after implantation. In addition, the scaffold can be cut preferably in a form upon request before being saturated by a physiological buffer for implantation.