发明名称 |
PHARMACEUTICAL GRANULES |
摘要 |
<p>A high speed agitation granulator method of preparing a substantially spherical granule for pharmaceutical use comprising a medicament for pharmaceutical use, wherein the medicament has an aqueous solubility of 0.01 to 0.30 g/ml, which method comprises introducing a mixture of medicament and excipients comprising at least 5% crystalline cellulose into the granulator and spraying on water or a mixture of ethanol and water as binder solution; a substantially spherical granule for pharmaceutical use comprising famciclovir and 5% or more crystalline cellulose, together with an optional coating; and a sachet containing a unit dose of famciclovir in the form of such granules.</p> |
申请公布号 |
EP0850048(B1) |
申请公布日期 |
2004.06.23 |
申请号 |
EP19960929522 |
申请日期 |
1996.09.04 |
申请人 |
NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. |
发明人 |
AKIYAMA, HIDERO;MATSUMOTO, ZENE;UENO, TAKASHI |
分类号 |
A61K9/16;A61K31/4415;A61K31/52;A61K31/522;A61K47/38;(IPC1-7):A61K9/16 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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