发明名称 |
NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED STEAP-1 USEFUL IN TREATMENT AND DETECTION OF CANCER |
摘要 |
A novel gene 08P1D4 (also designated STEAP-1) and its encoded protein, and variants thereof, are described wherein STEAP-1 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, STEAP-1 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer, the STEAP-1 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with STEAP-1 can be used in active or passive immunization. |
申请公布号 |
EP1429793(A2) |
申请公布日期 |
2004.06.23 |
申请号 |
EP20020773295 |
申请日期 |
2002.09.06 |
申请人 |
AGENSYS, INC. |
发明人 |
FARIS, MARY;GE, WANGMAO;RAITANO, ARTHUR, B.;CHALLITA-EID, PIA, M.;JAKOBOVITS, AYA |
分类号 |
A01K67/027;A61K31/7088;A61K31/7105;A61K35/14;A61K38/00;A61K39/00;A61K39/395;A61K45/00;A61K47/48;A61K48/00;A61K51/10;A61P35/00;A61P43/00;C07K14/47;C07K14/705;C07K14/72;C07K14/82;C07K16/30;C07K16/32;C07K16/46;C12N5/10;C12N15/09;C12P21/08;C12Q1/02;C12Q1/68;G01N33/566;G01N33/574;(IPC1-7):A61K35/14;C07K1/00;A61K39/40;C07K16/00;C07K14/00;C07K17/00 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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