| 发明名称 |
Dmt-Tic di- and tri-peptide derivatives and related compositions and methods of use |
| 摘要 |
A compound of formula:comprising the Dmt-Tic pharmacophore and related compositions and methods of use in the inhibition of the binding of an opioid receptor-binding compound with a P-glycoprotein, specifically hMDR-1, are provided.
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| 申请公布号 |
US6753317(B1) |
申请公布日期 |
2004.06.22 |
| 申请号 |
US20010814558 |
申请日期 |
2001.03.22 |
| 申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
LAZARUS LAWRENCE H.;SALVADORI SEVERO |
| 分类号 |
A61K38/00;C07D217/12;C07D217/14;C07K5/065;C07K5/087;(IPC1-7):C07K5/06 |
主分类号 |
A61K38/00 |
| 代理机构 |
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